Experimental Induction of Hypomagnesemia in Early-Weaned Calves

Experimental Induction of Hypomagnesemia in Early-Weaned Calves

Hamada Tatsuo, Tanabe Shinobu, Omori Akichiro, Kameoka Kenichi, Morimoto Hiroshi

Abstract

1. By feeding early-weaned calves (Nos. 9, 11, 19) a diet of roughage and a purified feed deficient in magnesium from 37 days of age, hypomagnesemia was experimentally induced.

2. Calf No. 9, which exhibited severe tonic convulsions at 65 days of age, rapidly recovered after intramuscular injection of 200 ml of 5% MgSO₄ solution. Plasma magnesium levels rose from 0.5 mg/100 ml (during convulsions) to 1.5 mg/100 ml 13 hours after injection.

3. Calf No. 11 was found dead at 67 days of age in a condition suggesting it had experienced pronounced convulsions.

4. Calf No. 19’s serum magnesium levels reached dangerous levels of 0.59–0.50 mg/100 ml between 79 and 107 days of age, but did not progress to convulsions caused by hypomagnesemia.

5. Plasma and serum calcium levels were not affected by the progression of hypomagnesemia and remained within the normal range. Therefore, the hematological profile in this experiment is considered as hypomagnesemia with normal calcium levels.

6. Preliminary results regarding magnesium levels in tissues were presented.

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早期離乳子牛における実験的低マグネシウム血症の作成 - 株式会社APAコーポレーション

浜田 龍夫, 田辺 忍, 大森 昭一朗, 亀岡 暄一, 森本 宏 抄録