Effect on Expression Wrinkles

KIWITA
Jan 15
2 min read

Updated: Jan 18

Test Number: OSA19020702

Evaluation of the Effect of

UMO Concentrated Solution on Expression Wrinkles

Test requester

APA Corporation

60-11 Tokuhara, Ishii-cho, Anjo City, Aichi 444-1201, Japan

Test Contractor & Test Facility

Kirei Test Lab Co., Ltd.2-11-6 Tomioka, Koto-ku, Haseban Building 3F, Tokyo

135-0047, Japan

Summary

The two-dimensional replica analysis of wrinkle area showed that after application of the test product, the relative wrinkle area was significantly lower compared to before application. These results suggest that UMO Concentrated Solution can reduce the visibility of expression wrinkles.

Test Product

UMO Concentrated Solution

Test Method

Application Sites
- One side of the outer eye corner (crow’s feet) was left untreated (control), and the other side was treated with the test product.
Acclimation
- Subjects rested for approximately 20 minutes in a room maintained at 21.0 ± 0.3°C and 45.0 ± 2.0% relative humidity to acclimate the skin to the test environment.
Wrinkle Induction and Measurement
- Before application and 20 minutes after application, subjects repeatedly moved the outer eye corner to create an expression wrinkle model.
- Photographs and replicas were taken for analysis.
- Two-dimensional replica analysis was used to evaluate the effect of the test product on expression wrinkles.

Results

Table 1 and Figure 1 show the relative wrinkle area before and after product application, with pre-application set as 100%.
Table 2 shows examples of the wrinkle analysis based on replicas.
Replica images, replica analysis images, and full-frame digital photos were submitted separately.

Table 1: Relative wrinkle area (%) before and after application (pre-application = 100%)

Measurement	Relative Wrinkle Area (%)	t-test
Pre-application	100.0 ± 0.0	—
Post-application	69.4 ± 22.4	*P = 0.038

*n = 5, mean ± standard error, paired t-test, P < 0.05

Figure 1: Relative wrinkle area before and after application by two-dimensional replica analysis

Table 2: Examples of wrinkle analysis before and after application based on replica analysis

Interpretation:

The application of UMO Concentrated Solution led to a ~30% reduction in visible expression wrinkle area, indicating its potential to improve the appearance of fine lines around the eyes.

Note: This paper is translated from the following URL. The content is provided for reference on the scientific research of the raw material only. Whether APA raw materials are used or not, we hope this research will help increase understanding and awareness of body minerals.